You'll need HID's Linux drivers to make this work. This may seem like a simple task, but the driver is not really obvious on the HID website. The CardMan 5321 product overview page has a link to the drivers download page, but rather then bringing you directly to the CardMan's drivers, it brings you to the page for every driver for ever HID reader. The first one is for Linux, which I think is where people get caught up.
The file I downloaded was
I didn't try the 64-bit version, so use with caution.
The file I downloaded was
ifdokrfid_lnx_i686-2.10.0.1.tar.gz
. Here's a screenshot of the download location (you have to do some scrolling to find it):I didn't try the 64-bit version, so use with caution.